Mucuna Pruriens – Review the Latest Research

Full Disclosure

Mucuna the pruriens (M. Pruriens) is a veg plant indigenous to the subtropical and tropical areas that include Africa, South America, and Asia. It belongs to the Fabaceae genus and is one of the kinds of Mucuna. M. Pruriens is usually known as velvet bean or cowhage.

M. Pruriens is classified as a legume, which is why it's frequently used nutritionally and medicinally, particularly in Ayurveda, the oldest Indian medical system.

This article will examine the evidence-based science behind the potential benefits and use of M. Pruriens.

M. Pruriens is present in food items or as an alternative supplement. It is thought to be a source of various bioactive substances and nutrients that improve human health.

Uses of Mucuna Pruriens

Supplements should be tailored to your needs and evaluated by a healthcare professional, such as a pharmacist or registered dietitian. Supplements are not to cure, treat, or prevent illness.

The seeds and the other components of M. Pruriens are believed to be a rich source of bioactive substances like:

  • Amino acids
  • Tannins
  • Polyphenols
  • Lecithin
  • Gallic acid
  • Beta-sitosterol

These and other substances in M. Pruriens are believed to have numerous health benefits.

Due to these results, M. pruriens is frequently employed in Ayurveda to treat:

  • Stomach upset
  • Snake bites
  • Pain
  • Rheumatic disorders
  • Gonorrhea
  • Gout
  • Dysmenorrhea (painful menstrual cramps)

Like other herbal remedies, scientific evidence has not confirmed health claims about M. Pruriens. Specific uses of M. Pruriens have been researched more than other uses.

Below is a brief overview of some research conducted on typical uses of M. Pruriens.

Brain-Protective Activity

M. Pruriens has a significant chemical known as levodopa (L-dopa) that is the precursor of dopamine. Dopamine is a neurochemical naturally produced by the body, which is often utilized to treat the conditions associated with Parkinson's disease (PD).3 Due to these results, research has looked into M. pruriens as an alternative treatment option for PD.

A look at the lab and human studies revealed that M. Pruriens could be a safe alternative to some prescription medications for PD. According to the study, M. pruriens has demonstrated anti-PD and brain-protective properties in human clinical trials.

Small human studies were the only ones reviewed, but. Studies of a larger scale are required to verify the effectiveness and security of M. Pruriens in PD.

Furthermore, M. pruriens products aren't well-regulated to ensure they don't contain harmful impurities or improper ingredients. There isn't a dose standard for PD.

Symptoms of Anxiety & Depression

There are some theories that M. pruriens improves various symptoms of depression and anxiety. However, only a few studies have been conducted to verify this theory.

In addition, the majority of available research has been done using animals as models. Although we can learn from animal research, we cannot apply these findings to humans.

A study showed that mice that had depressive symptoms were given M. Pruriens extract before performing different stress tests. The M. Pruriens extract was proven to possess antidepressant effects on mice during the tests. These findings are thought to result from compounds found in M. Pruriens that boost dopamine levels, such as L-dopa.

Another animal study showed that M. Pruriens worked as both an antidepressant and anxiolytic (antianxiety) in rodents. The study found that rats who were given M. Pruriens displayed less depressive behavior than rats who were not given M. Pruriens. The effects were attributable to the presence of L-dopa.

Although these results might be, human studies are required before M. Pruriens can be suggested as a possible alternative treatment option for depression and/or anxiety.

May Increase Fertility in Males

A few studies suggest a connection between M. the pruriens and male fertility.

In various lab research studies, M. pruriens has been proven to increase the rate of spermatogenesis (the production of sperm) and other indicators of healthy sperm. Animals rather than humans mostly observed these results.

A few human studies have been conducted on how to use M. Pruriens for male fertility.

Multiple studies presented two human trials. The review found that using M. Pruriens produced more healthy sperm profiles and increased fertility for infertile males. A study showed that M. Pruriens increased the quality of semen, the concentration of sperm, and motility.

It's important to remember that human studies were insignificant, and larger studies must be conducted to understand the role played by M. Pruriens in male infertility.

Heart-Protective Effects

L-dopa, an ingredient in M. Pruriens, is known to inhibit angiotensin-converting enzyme (ACE). In excess, ACE is present in the body, increasing the risk of developing hypertension (high blood pressure) and heart disease.

Triglycerides and high cholesterol are other risk factors for developing heart disease and high blood pressure. In rodents, M. pruriens extracts have proven effective in lowering cholesterol and triglyceride levels.

In a different animal study, rats suffering from hypertension were fed seeds of M. Pruriens or Moringa (an herbal remedy). Both plants produced blood pressure lowering effects, M. pruriens showed more heart-protective properties than moringa.

The results have yet to be replicated in humans. However, we can gain knowledge from animal and lab research, but human trials must be completed before M. Pruriens is suggested as a treatment for high blood pressure.

What Are the Side Effects of Mucuna Pruriens?

Some people experience side effects while taking M. Pruriens. Very few side symptoms have been identified for M. Pruriens. The potential side effects of this supplement are generally believed to be the result of L-dopa.

Common Side Effects

L-dopa use has been associated with numerous side consequences. These negative effects are more likely to occur with the short-term use of L-dopa.

Common L-dopa side effects include:

  • Nausea
  • Vomiting
  • Drowsiness
  • Dizziness
  • Headache

These effects aren't directly related to M. Pruriens but could be possible because of its L-dopa contents.

Severe Side Effects

Sometimes, L-dopa may cause severe adverse reactions, mainly when it is used in large doses or for a prolonged time.

Potentially serious side effects associated with L-dopa are:

  • Confusion
  • Hallucinations
  • Delusions
  • Agitation
  • Psychosis

However, these adverse effects have been only reported in conjunction with using L-dopa, not M. Pruriens. If the side effects persist or worsen, you should seek medical attention.

To minimize the chance of adverse effects, make certain to take M. Pruriens safely. Discuss with your healthcare professional the dosage and length of time you're supposed to use it.

Precautions

Certain people shouldn't use M. Pruriens because of illnesses or other causes. For instance, it's unknown whether M. pruriens is safe to use during pregnancy or nursing. Exposure to L-dopa might not be suitable for a fetus or infant. The best option is to avoid using M. pruriens in this scenario.

Research has not been conducted on the effectiveness and security of M. Pruriens in children. If you're considering having your child M. Pruriens, speak with your healthcare professional first.

Because M. Pruriens could decrease blood pressure, you might have to steer clear of using it when your blood pressure is low. M. Pruriens could cause blood pressure to be too low for some individuals.

Further research is required to determine what other groups must be cautious when using M. Pruriens. Discuss with your healthcare provider before taking M. Pruriens if you have medical issues or use prescription drugs.

Dosage: How Much Mucuna Pruriens Should I Take?

Always consult your doctor prior to using a supplement to confirm that the dosage and supplement are appropriate for your personal requirements.

Dosage guidelines haven't yet been established for M. Pruriens. This is because there is a general need for further research into the herbal remedy.

Many M. Pruriens studies have been done on animals, making it challenging to determine dosage guidelines for humans.

A handful of studies concerning the impact of M. Pruriens on PD are being conducted on human subjects. In a single study, patients suffering from PD received either a lower dosage of 12.5 milligrams for every kilogram of body mass (mg/kg) or a higher amount in the range of 17.5 mg/kg M. Pruriens powder six times throughout the study. Both doses improved PD symptoms.

As there is not much information on M. Prurien's dosage guidelines right now, it is recommended that you adhere to the dosage instructions indicated on the supplement's label. You may also consult a healthcare expert regarding safe and appropriate dosage.

What Happens If I Take Too Much Mucuna Pruriens?

There is a possibility of toxicity with the use of M. Pruriens due to its L-dopa contents. Sometimes, it is possible to get ill when you consume too many M. Pruriens, apply for too long, or eat the seeds in their raw form. The hairs on the seeds contain the compound mucunain, which can irritate the skin or cause tingling sensations.

Consuming raw seeds can cause diarrhea, nausea, vomiting, and even amnesia. This has been reported in sporadic instances.

Remember the fact that using M. Pruriens or L.-dopa excessively or in large doses could result in severe adverse reactions, such as hallucinations, psychosis, and confusion.

It's essential not to consume more M. Pruriens than necessary, as this could trigger adverse reactions or even worse.

Interactions

Similar to many other herbal remedies and supplements, M. pruriens can interact with some medicines and various nutrients and supplements.

However, interactions with M. Pruriens aren't documented.

A potential interaction could occur between M. Pruriens and antidepressants. Because M. Pruriens can also induce antidepressant effects, the drug, along with prescribed antidepressants, might not be a safe choice.

M. pruriens contains L-dopa, which is a commonly prescribed medication to treat PD as well as other neurological illnesses.

Doing M. Pruriens and L.-dopa together could increase the presence of L-dopa in your body. Consult a doctor regarding safe methods to use M. pruriens and L-dopa together.

Additionally, due to its potential effects on blood pressure, M. pruriens may interfere with medicines prescribed to lower it. Taking these two together can cause blood pressure to become too low.

There could be other interactions. If you are taking any medication or other herbal supplements, discussing any possible interactions with a medical professional before beginning M. Pruriens or any other supplement is suggested.

It is important to read carefully the ingredients list and the nutrition facts section of the supplement to determine what ingredients are included and the amount of each ingredient. Check the labels of supplements with your healthcare professional to discuss potential interactions with other foods, supplements, or medications.

How to Store Mucuna Pruriens

It's essential to store your supplements to help to maintain their quality properly.

Keep M. pruriens supplements in an air-tight, dry area like the pantry or cabinet. Keep them away from direct sunlight. As with others, M. Pruriens must not be refrigerated.

It is best to store supplements in the original containers. Be sure your lid for the container is sealed with air.

The store should be kept away from M. pruriens in an area that isn't easily accessible by pets or children. Might accidentally consume large doses of the supplements.

Throw away M. Pruriens' supplements when they reach their expiration date or if they exhibit any indications of spoilage.

Similar Supplements

Many supplements are available today, and a few are like M. Pruriens. The supplements could contain the same ingredients or operate in ways like M. the pruriens.

Supplements that resemble M. Pruriens are:

  • Glutathione: Glutathione is a natural antioxidant being studied for its possible involvement in Parkinson's disease. Although it does not appear to improve the quality of life or mental functioning, glutathione has been proven to enhance motor function in patients with PD. Further research is required in this field.
  • Rhodiola rosea Rhodiola rosea is a plant and adaptogen, naturally occurring substance thought to help reduce stress.
  • Ashwagandha: Ashwagandha (also known as Withani somnifera) has been used for ages in Ayurvedic treatment to boost male fertility.
  • Green tea drinking can reduce the risk of developing high blood pressure. A recent study found that consuming green tea over a period of time decreased the risk of having high blood pressure by 6 percent. The effects could originate from the catechins present in green tea.

It's not recommended to take a variety of supplements or herbs simultaneously, especially with the same health problem. Consult with your healthcare professional and a registered dietitian nutritionist to help you decide what supplements or herbs will be most beneficial for you.

FREQUENTLY ASKED QUESTIONS

Does Mucuna pruriens increase dopamine?

M. Pruriens is a source of L-dopa (levodopa), a compound required to produce dopamine within the body. Dopamine is a neurotransmitter (brain chemical) that helps to improve motivation and mood. A few studies have shown that M. Pruriens could increase the levels of dopamine and, therefore, could help treat certain disorders like depression and Parkinson's.

Does Mucuna pruriens raise serotonin levels?

There isn't any evidence that suggests M. Pruriens can increase serotonin levels. Much like dopamine, serotonin is a neurotransmitter that affects mood. In spite of the absence of evidence, many people believe that M. Pruriens can increase serotonin since it's known to boost dopamine levels.

Can Mucuna pruriens cause anxiety?

Research suggests that M. is pruriens could reduce anxiety symptoms but not trigger them. While no human studies have yet been completed, animal studies have revealed a positive effect of M. Pruriens on anxiety. The effects are believed to originate from the L-dopa.

Is Mucuna pruriens a stimulant?

The evidence isn't there to suggest to suggest that M. pruriens acts as a stimulant. Although M. Pruriens can be an antidepressant, it isn't the same thing as a stimulant.

Stimulants are thought to boost the amount of energy you have and also reduce both physical and mental fatigue. They are commonly employed to treat ailments such as Attention deficit hyperactivity disorder (ADHD) and narcolepsy.

Is Mucuna pruriens safe?

M. pruriens is generally thought to be safe for most people. However, only a little safety research has been conducted on the herb, and patients with specific conditions might require caution when using it.

Due to the L-dopa content, it is possible to be prone to side effects such as nausea or vomiting, drowsiness, or headache if you are taking excessive amounts of M. Pruriens.

Sources of Mucuna Pruriens & What to Look For

Many people take M. Pruriens to supplement their diet, but many prefer to obtain it from food items instead.

It's important to note that research hasn't confirmed many health benefits of M. Pruriens. However, there are benefits to taking M. Pruriens, whether as a supplement or as a food item.

Food Sources of Mucuna Pruriens

As a legume, M. Pruriens is a legume that can be eaten if cooked appropriately.

Generally, M. pruriens seeds are the central part of the plant consumed. It is possible to roast the seeds, consume them in their natural form, or incorporate them into different recipes. M. Pruriens seeds are a regular part of the diet of some regions in Asia and Africa. Some researchers have suggested that M. Pruriens seeds might be cultivated to reduce the amount of L-dopa present in their food and make them safer to eat.

M.pruriens seeds are believed to be rich in a variety of nutrients, such as:

  • Fiber
  • Protein
  • Carbohydrates
  • Fatty acids
  • Potassium
  • Calcium
  • Iron
  • Zinc
  • Manganese
  • Magnesium
  • Amino acids

The other nutrients found in M. Pruriens seeds make them a nutrient-rich food.

It's important to mention that M. Pruriens seeds may be hard to locate in the stores. In the end, it might be necessary to purchase the seeds on the internet.

Mucuna Pruriens Supplements

M. Pruriens supplements are available in powders, capsules, and liquid extracts. Other forms are also available, but they aren't easy to find.

Concerning where to purchase M. Pruriens, the Internet is a good option. M. Pruriens supplements can be purchased through Amazon and other sites. It is possible to find M. Pruriens' supplements in different shops for supplements, nutrition, or natural food stores.

Many M. Pruriens products are vegan, organic, or gluten-free. If you're on a vegan eating plan, be aware that some capsules might be made from gelatin, which isn't a vegan-friendly product. Make sure you check the label on the supplement to see the specifics.

Dietary supplements are not controlled like other drugs regulated in the United States. They could create interactions with medications or pose different safety issues. This is why it's crucial to be aware of what to look out for when selecting a supplement, like third-party testing, possible drug interactions, and many more.

Summary

Mucuna the pruriens (M. the pruriens) is an evergreen vegetable plant that produces legumes.

More research is required on the health benefits that could be derived from M. Pruriens. There is evidence that suggests it might help with Parkinson's depression, anxiety, and Parkinson's disease, as well as male infertility and high blood pressure.

L-dopa is the principal compound that is the main ingredient in M. pruriens and is believed to be responsible for some of the advantages associated with M. pruriens. However, taking L-dopa for prolonged periods or using excessively high doses could raise the chance of adverse effects.

If you're considering experimenting with M. Pruriens, make sure to conduct your research and find top-quality, reliable products. It is also possible to talk to your doctor to learn more about supplements and if M. Pruriens is the right choice.

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