Immuno Defense 4x: Review JayLab Pro Smart Immune Supplement

Immuno Defense 4x by JayLab Pro Nutrition and Jayson Hunter is a smart immune health supplement offering a science-backed natural immunity boosting formula to overcome inflammation and aging.

Full Disclosure

Immuno Defense 4x is a nutritional supplement from JayLab Pro.

By taking Immuno Defense 4x daily, you can purportedly support your immune system, making it easier to defend your body against colds, flus, and other issues.

Let’s take a closer look at how Immuno Defense 4x works – and see if it really supports your immune system as advertised.


What is Immuno Defense 4x?

Immuno Defense 4x is a supplement sold online through

Like other immune supplements available today, Immuno Defense 4x claims to support immunity in multiple ways. You take it daily, and your body is better able to fight off infections and recover from cold or flu symptoms.

In fact, the makers of Immuno Defense 4x claim their supplement is crucial for “keeping the common cold, the flu, or other deadly viruses – at bay.” The creator of the formula claims this supplement has kept his family “illness-free” for the last 5 years.

Obviously, all immune system supplements make similar claims, claiming to supercharge immunity and help your body defend itself against all types of issues. But does Immuno Defense 4x actually work? Let’s take a closer look at how Immuno Defense 4x works – and the story behind the formula.

The Story Behind Immuno Defense 4x

Immuno Defense 4x was formulated by a registered dietitian named Jayson Hunter. Jayson is the owner of JayLab Pro Nutrition.

Jayson claims Immuno Defense 4x has kept his family illness-free for the last five years. Now, he wants to share that immune supporting system with the world.

Jayson has a degree in Nutrition and Dietetics from Illinois State University. Today, he sells supplements online targeting various health goals.

On the Immuno Defense 4x sales page, Jayson tells the story about traveling on a plane to Chicago to speak at a nutrition conference – and getting sick at the worst time.

In the days leading up to his flight, Jayson developed a nasty head cold that plugged his ears, stuffed his sinuses, and gave him a congestion headache. Jayson, however, still wanted to attend the conference.

Instead of giving in to the illness, Jayson took his secret Immuno Defense 4x formula to recover more quickly. Now, he wants to share that formula with the world, helping others support their immune systems against deadly illnesses.

How Does Immuno Defense 4x Work?

Immuno Defense 4x uses similar ingredients to what we see in other immune supplements, including bromelain, vitamin D, and quercetin, all of which are linked with immunity in various studies.

The formula is called ‘4x’ because it uses four active ingredients, including the three listed above and one extra ingredient called whole food fermentate. You can find vitamin D, quercetin, and bromelain in any immune supplement, although whole food fermentate is less common.

Some of the advertised benefits of Immuno Defense 4x include:

  • Supports a healthy immune system
  • Strengthens innate immunity and adaptive immunity
  • Strengthens the mucosal immune berry
  • Clinically shown to activate natural killer (NK) cell activity within 2 hours of ingestion

Whole food fermentate is a special type of yeast typically used as food for livestock. It’s been shown to keep livestock healthy and disease-free.

Eventually, researchers analyzed illnesses among factory workers who worked in whole food fermentate preparation plants. They found a low risk of illness compared to the general population.

Here’s how the Immuno Defense 4x sales page explains the benefits of whole food fermentate yeast:

“The plant workers handling this yeast had far stronger immune systems than the average office worker. The office workers, not exposed to this yeast, had sick rates that met the national average…And would have put a hefty toll on the current health insurance policy.”

Jayson claims this yeast is “so effective at boosting your immune system” because it’s linked with a rapid increase in ‘killer T cell’ activity in your immune system. These cells are the parts of your immune system that fight off foreign invaders, making it easier to recover from illness.

Jayson also claims the whole food fermentate yeast “raises antioxidant levels,” which “lowers the same chronic inflammation that leads to ‘inflamm-aging’,” among other benefits.

In more simplistic terms, Immuno Defense 4x claims to contain ingredients that support your immune system from multiple angles, making it easier for your body to function effectively.

Immuno Defense 4x Ingredients

Immuno Defense 4x contains four active ingredients linked with immunity. We’ll summarize each of those ingredients below and how they work according to Jayson and his team:

Whole Food Fermentate (EpiCor): This is the unique type of yeast mentioned above. The makers of Immuno Defense 4x claim this yeast is linked with higher antibody levels in your immune system and better killer T cell counts, among other benefits. By taking 500mg of whole food fermentate per day, you can enjoy powerful benefits.

Quercetin: Quercetin is a natural chemical found in dark chocolate, olive oil, grapes, dark cherries, apples, onions, and red wines. Today, growing research shows that quercetin is linked with everything from better immunity to anti-aging effects. Some cold and flu supplements, for example, contain a rich dose of quercetin to help with immunity. Jayson claims that the quercetin in Immuno Defense 4x can actually “lower the age of your immune system,” making it more resistant to issues.

Vitamin D: If you’re going to take one vitamin to support your immune system, make it vitamin D. Studies show that people deficient in vitamin D have weaker immune systems. Vitamin D is a fat soluble vitamin that you typically get from sunlight. If you aren’t getting enough sunlight, or if you live in the northern hemisphere during the winter, then a vitamin D supplement can be crucial for immunity.

Bromelain: Bromelain is an enzyme found in high levels in pineapple. Some studies show that bromelain can help your immune system deal with colds, flus, and other issues. Jayson claims the bromelain in Immuno Defense 4x works by “boosting the power of quercetin,” providing synergistic benefits across the formula.

JayLab Pro Nutrition lists all ingredients and dosages upfront, making it easy to compare Immuno Defense 4x to scientific studies and competing supplements. We know there’s 500mg of whole food fermentate (in the form of EpiCor), for example, along with 500mg of quercetin, 150mg of bromelain, and 1,000 IU (166% DV) of vitamin D3, all of which are considered strong doses.

Scientific Evidence for Immuno Defense 4x

JayLab Pro Nutrition has not invested in any clinical trials or scientific studies on its formula, nor do they publish any research online. However, the company does cite third party studies performed on individual ingredients in Immuno Defense 4x, including studies linking these ingredients with immune supporting benefits.

First, hundreds of studies have confirmed the connection between vitamin D supplementation and immunity. As this 2011 review study explained, vitamin D has a clear role in immune system effectiveness, and immune cells need vitamin D to function correctly. Vitamin D particularly impacts immunity via bone and calcium homeostasis. It also interacts with immune cells like B Cells, T cells, and antigen presenting cells. For all of these reasons, many doctors recommend taking vitamin D supplements regularly to support immunity.

Of course, you can find vitamin D supplements for $5 at any pharmacy or supermarket. What does science say about other ingredients in Immuno Defense 4x?

EpiCor is a whole food fermentate formula created by Embria Health Sciences. Embria Health Sciences has conducted multiple studies on EpiCor linking it with various effects. You can view a summary of Embria’s human clinical trials here.

Some of the notable results from Embria’s research include:

In a study on 22 healthy subjects, participants significantly increased SlgA, an antibody integral to your immune system, after taking EpiCor

In a double-blind, placebo-controlled trial on 25 healthy subjects bweten ages 18 to 43, researchers found a connection between EpiCor and immune system function; over a five-week period, researchers found that EpiCor positively impacted SlgA and IgE, antibodies associated with crucial immune function

Both flu-vaccinated subjects and non-vaccinated subjects improved immunity after taking EpiCor, with both groups, significantly reducing the incident of cold and flu symptoms after taking EpiCor

Other studies have linked EpiCor to better inflammatory effects, better immune cell activity, and overall better immune function, among other benefits. Some of these studies involved 80+ human participants, which is much better evidence than most supplements have. Most studies also used 500mg of EpiCor – the same dose in Immuno Defense 4x.

This 2016 study published in Nutrients found a significant connection between quercetin, inflammation, and immunity, although researchers cautioned that more research was needed to verify these effects.

Similarly, this 2018 study found a potential connection between bromelain and immunity, suggesting bromelain could have anti-inflammatory, anticancer, and immunomodulatory effects, among other benefits. Researchers found evidence bromelain could increase wound healing and circulatory health, for example, while supporting overall immunity.

Overall, Immuno Defense 4x contains four of the most proven ingredients for immunity. The company discloses all dosages upfront, and the supplement contains similar dosages to what researchers have used in peer-reviewed studies. For all of these reasons, science tells us Immuno Defense 4x should work as advertised to support immune health.

Immuno Defense 4x Pricing

Immuno Defense 4x is priced at $45 per bottle, although the price drops as low as $30 per bottle if ordering multiple units:

  • 1 Bottle: $44.95
  • 3 Bottles: $114.95
  • 6 Bottles: $179.95

All prices include shipping to the United States.

Each bottle of Immuno Defense 4x contains 60 capsules (30 servings). You take two capsules per day to support immunity.

If you buy the 3 bottle or 6 bottle packages, you also get a free coaching session with Jayson Hunter.

All purchases also include two free eBooks, including Your Immunity Support Playbook and Your Immunity Support Recipes.

Immuno Defense 4x Refund Policy

Immuno Defense 4x comes with a 60 day money back guarantee. You can request a complete refund within 60 days with no questions asked.

Just contact the company, then return your bottle to complete the refund process. View full details about the refund policy here.

About JayLab Pro Nutrition

JayLab Pro Nutrition is a supplement company owned and operated by certified dietitian Jayson Hunter.

The company offers a range of supplements targeting different health goals, including Immuno Defense 4x (for immunity), LeptiSense (for weight loss), Ultra-Cleanse Detox (for detoxification), and JayLab Pro Probiotics (for digestion), among other products.

pro grade

You can contact JayLab Pro Nutrition via the following:

Phone: 1-888-943-8776

Email Form:

Mailing Address: 2025 Zumbehl Rd. PMB13, St. Charles, MO 63303

Final Word

Immuno Defense 4x is an immune supplement priced at a reasonable rate. The supplement contains powerful doses of four proven immune supporting ingredients, including EpiCor, bromelain, quercetin, and vitamin D. All four of these ingredients have been shown to work at the same doses used in Immuno Defense 4x.

If you want to support immunity, then Immuno Defense 4x is one of the better supplements available online today. The supplement also comes with a generous refund policy, making it easy to receive your money back if Immuno Defense 4x does not support your immunity as advertised.


Live Healthier
Advanced Living is a leading lifestyle wellness enhancement movement that highlights health awareness, provides educational research and delivers perpetual knowledge on how to live your best life in 2024 and beyond so you can master the art of aging gracefully in this lifetime. From high energy insights on trending news to truth-seeking analysis for supplement reviews, Advanced Living exists to optimize your well-being universe and act as a genuine guide for personal transformation, spiritual enlightenment and essential wholeness. may receive a small reward on product purchases using links within reviews. For optimal transparency, see the full disclosure on how this process works to support our team’s mission of creating Advanced Living for you. content provides generalized information only for education and entertainment. In no way is the content here a substitute for qualified medical advice. Always actively seek a professional dietitian, certified nutritionist, licensed specialist or your doctor for specific consultation before using any supplement our team reviews.

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