Curcumin – Latest Research Included

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Curcumin is what?

Curcuma longa flowers are a plant belonging to the ginger family. It is most well-known as turmeric, a spice commonly used in curry. Turmeric is a polyphenol with anti-inflammatory properties and the capability to boost the quantity of antioxidants your body produces.

Curcuminoids and curcuminoids found in turmeric are extracted to make supplements with much greater potency than turmeric. However, curcumin consumed orally is not well absorbed by digestion, so various formulations have been developed to enhance the bioavailability of curcumin.

What are the primary benefits of curcumin?

Curcumin supplementation is proven to reduce specific markers of inflammation and boost the level of antioxidants produced by the body. Curcumin, however, has only a slight effect on the inflammation markers in those suffering from chronic inflammation.

It is imperative to conduct more research regarding curcumin's use in a wide range of health conditions. However, the present evidence suggests modest to moderate improvement in depression symptoms and moderate to substantial improvements in the quality of life and pain in osteoarthritis. Curcumin has also shown promise in treating an inflammatory bowel disease called ulcerative colitis. However, more studies are needed to establish the most effective dose and route of administration.

Improved blood lipids, indicators of glycemic management, liver enzymes, blood pressure, and weight loss have been seen when curcumin supplementation is used. However, the research on the effects of curcumin is often inconsistent, and more high-quality, controlled studies are randomized to reach a definitive conclusion.

What are the main disadvantages of curcumin?

One of the most significant disadvantages of curcumin is that it is not readily absorbed when inhaled orally.

Doses of up to 8 grams daily of curcuminoids haven't been associated with significant adverse reactions in humans. However, extensive long-term studies are required to confirm the absence of adverse reactions. Studies that have used high doses of curcumin have revealed a few mild negative effects, like headache, nausea, diarrhea as well as skin rashes, and yellow stool. Utilizing curcumin in conjunction with piperine (a extract of black pepper) could cause more the risk of adverse reactions to curcumin due to piperine's ability to increase the intestinal permeability. Not all curcumin-based formulations have been tested for safety to the same extent.

What is the function of curcumin?

Curcumin's beneficial potential appears to be mostly due to its antioxidant and anti-inflammatory properties. These characteristics are brought about by curcumin's direct and indirect interaction with and modulation of a variety of molecular targets, such as enzymes, transcription factors, cell cycle protein receptors, cell surfaces, adhesion proteins, growth factors, and protein kinases.

What are the other names that can be used for Curcumin?

Be aware of the fact that Curcumin is also referred to as:

  • Extract of Turmeric
  • Curry Extract
  • Curcuma
  • Diferuloylmethane
  • JiangHuang
  • Curcuma Longa
  • 1 7-Bis(4-hydroxy-3-3methoxyphenyl) hepta-1 6-diene-3 5-dione
  • Turmeric

Curcumin is not to be misunderstood with:

  • Curry (meal preparation utilizing Turmeric)
  • Tree Turmeric (a term used to describe Berberis aristata)

Dosage information

The recommended dose of curcumin to treat inflammation may vary. Research has found daily doses that range from 300 to 4000 mg, depending on the particular condition. When taken orally, curcumin can be absorbed poorly. The two most frequently used and frequently studied methods to increase absorption are to mix curcumin with piperine (a black pepper extract) or combine the two with other lipids (e.g., BCM-95(r) as well as Meriva(r)).

To complement curcumin with piperine, you should take 500 mg of curcumin along with 5-6.7 milligrams of piperine three times a day to get a total dose of 1,500 mg of curcumin and 15-20 mg of piperine a day.

To complement BCM-95(r), a patent-pending combination of curcumin and essential oils, you should take 500 mg twice daily for a total of 1000 mg per day.

To enhance Meriva(r), a patent-pending mixture of curcumin and lecithin, you can take 200-500 mg two times a day for a total daily intake of 400-1,000 mg.

Curcumin can be purchased in capsules, tablets, powder, soft gels, and drops. It is typically consumed with food.

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