The process of aging is one of the tragic yet necessary facts. Although we may be able to disguise wrinkles for a few years, we’ll all begin to feel the consequences of aging sooner or later.
Researchers studying longevity have been looking for compounds that might extend our life span (how long we live well). Additionally, NMN supplements are touted as among the most promising drugs for aiding in healthy old age.
Consuming NMN supplements can boost NAD+ levels. This has been proven to provide powerful health benefits compared to animal research. Increasing NAD+ levels induces a shift within our cells that improves longevity, including expanding energy production and regulating cell repair.
Naturally, there’s an enormous amount of curiosity about NMN supplements, so it’s not difficult to find various brands available on the market. The most effective NMN supplements will have the purest ingredients without unnecessary additives. Certain NMN supplements may also include additional well-known anti-aging ingredients that maximize the overall benefits.
We’ve created an overview of the top NMN supplements in relation to ingredient quality and dosage, as well as cost-effectiveness.
WHAT MAKES A TOP NMN SUPPLEMENT?
When you are deciding on the top NMN supplement, there are only certain aspects you must know about.
Purity
The most effective NMN supplements should have at least 98 percent purity NMN.
Dose
The optimal NMN dose isn’t established and will vary for each person. Studies on research typically use doses of 300-900 mg and this is the dosage range that you’ll typically see in the most effective NMN brands.
Quality
Be sure to look for companies that produce NMN in a GMP-accredited (good manufacturing practices) facility. Some brands also ship their products to third-party tests to ensure quality and dosage. You should avoid any fillers or packing materials to ensure you consume only the required ingredients.
Other ingredients that fight aging
While NMN is considered one of the top anti-aging substances available, other ingredients have been proven beneficial. This is why certain supplements mix NMN with other anti-aging components such as Resveratrol, Fisetin, Spermidine, Quercetin, and other antioxidants.
In this regard With this in mind, here’s a short listing of some of the top NMN supplements currently available.
TOP PICK OF THE 5 BEST NMN SUPPLEMENTS
#1 GENUINEPURITY LIPOSOMAL NMN
NMN Purity: 96.40%
NMN dose: 250mg
Quality:
- Pure NMN Content: GenuinePurity™ Liposomal NMN features pharmaceutical-grade NMN, ensuring high purity and potency.
- Clinically Studied Doses: Each dose contains 250mg of NMN, the amount proven effective in scientific studies.
- Liposomal Encapsulation Technology: Enhances absorption and effectiveness by protecting NMN from stomach acids and improving cellular uptake.
- cGMP-Certified Manufacturing: Produced in the USA in certified facilities to maintain consistent high quality.
- Quality Assurance: Backed by a 97-day money-back guarantee, affirming the confidence in the product's quality and effectiveness.
Pricing Overview:
- 1 Bottle – $69.95 (Save $10.00)
- 3 Bottle – $199.95 (Save $39.90)
- 6 Bottle – $349.95 (Save $129.75)
GenuinePurity™ Liposomal NMN stands out in the crowded market of health supplements by offering a scientifically-backed solution designed to enhance lifespan and improve overall health. This product specifically aims to boost Nicotinamide Adenine Dinucleotide (NAD+) levels in the body, a critical coenzyme involved in over 500 cellular processes including metabolism, DNA repair, and immune function. With age, NAD+ levels naturally decline, leading to various aging symptoms and reduced cellular function.
What sets GenuinePurity™ Liposomal NMN apart is its cutting-edge delivery system. Traditional NMN supplements suffer from poor bioavailability, as stomach acids degrade the NMN before it can be effectively absorbed. To overcome this, GenuinePurity™ utilizes a sophisticated Liposomal Encapsulation Technology. This technology encapsulates NMN in liposomes, protective bubbles that shield the molecule from harsh stomach acids and enhance its absorption into the bloodstream. This method not only protects the integrity of NMN but also improves its solubility and cellular uptake, ensuring that the body can efficiently convert NMN into NAD+.
Each dose of GenuinePurity™ Liposomal NMN contains 250mg of pure NMN, adhering to clinically studied amounts that guarantee effectiveness. The product is manufactured in cGMP-certified facilities in the USA, ensuring high-quality and consistent results. Additionally, it comes with a robust 97-day money-back guarantee, allowing customers to try the product risk-free.
Moreover, GenuinePurity™ proudly displays a Certificate of Authenticity with each product, confirming the purity and dosage of NMN, setting a benchmark of trust and reliability in a market where many supplements fail to deliver on their promises.
By choosing GenuinePurity™ Liposomal NMN, consumers are not just purchasing a supplement; they are investing in a scientifically validated pathway to potentially extend their healthspan and achieve a better quality of life as they age.
#2 OMRE NMN + RESVERATROL
NMN Purity: 98%
NMN dose: 500mg
Quality:
- Made in the USA
- GMP certified facility
- Third-party testing
- There is no silicon dioxide
- 30-day money-back guarantee
Others ingredients
- Resveratrol 500mg (98% purity)
- BioPerine(r) 5mg
Price: $59.97
OMRE is a blend of high-purity NMN with Resveratrol, a potent anti-aging ingredient. Additionally, it contains BioPerine(r), a patent-pending bioavailability booster. Essentially, BioPerine(r) improves the absorption of other ingredients. Studies have shown it can possibly increase the absorption of resveratrol up to 10 times.
OMRE makes use of veggie capsules and does not contain additives such as silicon dioxide and magnesium stearate. Additionally their product is produced by the USA in a facility which is FDA and GMP certified.
Find the most current price on the OMRE site
#3 WONDERFEEL YOUNGR NMN
NMN Purity: 98%
NMN dose: 900mg
Quality:
- Veggie capsule
- Third-party testing
- Made in the USA
- A high dose of NMN
Others ingredients
- Resveratrol 100mg (98% purity)
- Olive fruit extract 50mg
- Ergothioneine 4mg
- Vitamin D 20mcg
Price: $88
Wonderfeel is packed with a whopping 990mg of NMN in each serving. It also contains 100mg of Resveratrol and 50mg from Olive fruits extract and 4 mg of Ergothioneine and vitamin D. It’s advertised as a longevity supplement that is able to cover all angles.
They claim their patent-pending formula is based on the “multi-targeted method to protect against and slow down the process of biological aging at the level of the cell.”
Like you’d expect from the name of a top brand, their product is made in a GMP accredited facilities located in the US and they stay clear of artificial flow agents as well as animals-based capsules.
The dose of 900mg of NMN is definitely on the higher side of the recommended dosage, which could be too excessive for sure. If you’re trying to get the maximum NMN dosage Wonderfeel is an excellent alternative.
Get the latest prices on Wonderfeel site
#4 RENUE BY SCIENCE LIPOSOMAL NMN
NMN Purity: 98%
NMN dose: 500mg
Quality:
- Liposomal NMN
- GMP certified facility
- Third-party testing
- There is no silicon dioxide
Price: $84.95
Renue by Science uses an liposome formulation based on powders to improve absorption. Liposomes are spheres made of fat that contain ingredients, which enhances absorption of fat-soluble molecules.
They also say the delivery system safeguards NMN from digestion enzymes. This unique delivery method is a high price that might not be appropriate to everyone’s budget. But, it’s an extremely rating NMN supplement from a well-known brand.
Find the most current price on the website of RENUE
#5 PRO HEALTH LONGEVITY NMN
NMN Purity: 99%
NMN dose: 500mg
Quality:
- 75-day money-back guarantee
- Made in the USA
- Third-party tested
- Silicon dioxide and silicon dioxide
Price: $58
ProHealth makes use of a patented
NMN supplier from Uthever that claims to be 100% purity. The supplement doesn’t contain any other additives such as magnesium Steararte. Instead, they utilize brown rice powder that is a natural replacement.
Additionally the fact that their supplements are manufactured from the USA in an FDA and GMP certified facility. This means that they meet all the criteria in terms of high-quality and pure. The only drawback is that they’re priced at the top end of the market. However, they are what you get for your money.
If you’re looking for ProHelath supplements, the company sell a wide range of NMN forms, including capsules, lozenges, and powders that can meet all requirements of the consumer.
Find the most current price on the the PROHEALTH site
#6 DOUBLE WOOD NMN
NMN Purity: 98%
NMN dose: 250mg
Quality:
- Bulk discount
- Made in the USA
- Third-party testing
Price: $49
Double Woods is a company which has been manufacturing premium supplements for many years. Double woods is a brand with a wealth of experience and a solid reputation.
We’re glad they do not use magnesium stearate and choose to use the rice flour alternative. The NMN supplement comes with a 250mg dosage per serving, which is lower when compared to other supplements that are mentioned in this article.
The most significant issue is that the capsules they utilize contain gelatin and aren’t suitable for people who are vegan or vegetarian. Concerning the high-quality, their products are tested by third parties and produced from the USA.
Find the most current price on DOUBLEWOOD’s website
WHAT IS NMN?
NMN is the abbreviation for nicotinamide monnucleotide. It’s an equivalence of Vitamin B3.
In actuality Vitamin B3 is transformed into NMN in a variety of steps. First the vitamin B3 is transformed into Nicotinamide Riboside (NR). Then 2 NR molecules are merged to create NMN.
Many people question whether NMN as well as vitamin B3 is one thing. They aren’t. Vitamin B3 is only one of the essential building blocks to create NMN.
In our cells in our cells, in our cells, two NMN molecules combine to create NAD+. That’s the reason that taking NMN supplements increases NAD+ levels.
Furthermore, NAD+ plays a role in numerous cells, such as the process of metabolizing energy as well as DNA repair. As we age, amounts of NAD+ in our bodies decline, causing an increase in these processes, and possibly contributing to the development of age-related illnesses.
NMN SUPPLEMENTS – WHAT ARE THEY GOOD FOR?
Over the past 20 years, a number of studies on animals have proven that increasing NAD+ levels can have an important positive effect on the signs of ageing.
WHAT ARE THE HALLMARKS OF AGING?
The list of factors can be extensive. However, it boils down to the following four elements that are the most important signs of aging you need to know about:
- Increased levels of Inflammation
- Sensitivity to insulin is reduced
- Reduced mitochondrial function
- Gene instability and impairment of DNA repair
There are numerous NAD+ boosting ingredients. However, NMN is regarded as the most potent because it’s directly related of NAD+.
The study into the advantages of NMN supplementation in humans is currently in progress. However, in studies on animals, it’s proven to delay and even reverse the signs of the aging process.
Although it’s still not proven beneficial in the human body, it’s not without plenty of expectations for the potential of NMN.
DOES NMN WORK?
Human clinical trials examined precisely this issue in 2024. The study included 80 healthy middle-aged adults for a 60-day trial using a once-a-day oral dosing regimen of 300 mg placebo 600 mg, 300 mg, or the 900 mg NNM.
They analyzed the following items:
- Blood NAD+ levels were measured.
- Tolerability and safety when taking NMN supplements
- The test measures physical performance using the standard 6-minute walk test.
- Age of blood biological development
- Insulin Sensitivity to Insulin
The results were intriguing. What they discovered after 60 days
- NAD+ levels were significantly elevated over placebo at all dosages (300-900mg)
- No reported side effects. Well-tolerated
- The 6-minute walk test performed better by all groups when as compared to placebo, with an increase of 600mg per day dosage.
- The biological age of blood increased in the placebo group, but remained the same for all patients who took NMN (all dosages).
- Insulin sensitivity: no significant difference in the people who take NMN when compared to placebo.
Incredibly, a substantial benefit was observed even at a dose of 300mg for most aspects. A dosage of 600mg produced the most effect upon physical performances.
It’s important to note that this was a tiny study with only 80 participants. This means that a lot more scientific research and clinical trials is needed. But the initial results are extremely promising.
WHAT’S THE IDEAL NMN SUPPLEMENT DOSAGE?
It’s unclear what the optimal NMN dosage is for a supplement. Based on the research that was mentioned earlier, it’s evident that even a lesser dosage of 300mg can provide substantial advantages over placebo.
The most effective NMN supplements are those that have an amount of about 500mg. This is around between the spectrum utilized during research.
The optimal NMN dose is likely to differ from person to person.
The most reliable method to determine the ideal NMN dose is to examine your blood parameters as well as your biological age. It is much simpler said than done, and may be costly.
You could also try a smaller dosage and then check out how you react.
IS IT SAFE TO TAKE NMN DAILY?
As we’ve mentioned before the fact that there’s only some supplements scientific research and clinical conducted in humans, and the majority of them have looked at providing daily NMN over the course of 3-4 months.
So far, no specific issues have been identified, and more studies are in progress. The only thing we know is long-term safety findings until at the very least a few years to come.
HOW LONG DOES IT TAKE FOR NMN TO START WORKING?
NMN begins to boost NAD+ levels just a couple of weeks, but most definitely within 30 days.
The time it takes for this information to manifest into visible and quantifiable health benefits is unknown.
The study we discussed above reported improved walking speed and blood biomarkers for aging observed after two months.
In reality, the benefits that are noticeable are likely to take more time than that. Like everything health-related there aren’t any immediate changes!
IS IT BETTER TO TAKE NMN SUPPLEMENTS IN THE MORNING OR AT NIGHT?
Harvard Professor Dr. David Sinclair and his colleagues have recommended taking NMN supplements in the early morning.
Our cells produce more NAD+ during the early morning and then levels drop when it’s night time.
In order to align your cells’ biology and to be in sync with your cell biology, using NMN supplements early in the day is more sense.
HOW WELL ARE NMN SUPPLEMENTS ABSORBED?
Contrary to other supplements in which absorption can be a problem, NMN can be absorption from the gut into the blood circulation in a matter of 2-3 minutes and is then absorbed into the cells in just 15 minutes.
Certain brands offer NMN in a liposomal form, that can boost absorption more. However, even powdered capsule NMN supplements are highly absorbent.
WHAT IS THE BEST WAY TO GET NMN?
Finding a sufficient quantity of NMN through food is a challenge.
In perspective, 100 g of avocados and tomatoes contain between 0.36 and 1.6mg of NMN.
NMN supplements however con,tain up , to 300-1000mg NMN.
So an average avocado of 200g contains approximately 2 mg of NNM. It is recommended to consume around 250 avocados to get 500mg of NMR.
Of course, an optimum diet that includes a variety of portions of vegetables and fruits is essential for overall health. However, the most effective way to obtain enough NMN to have an impact is to take supplements. It’s challenging to get an adequate amount of NMN from your diet, which will impact NAD+ levels.
HOW TO CHOOSE THE RIGHT NMN SUPPLEMENT
CONSIDER YOUR GOALS
Before you search, consider the goals you want your NMN supplement to accomplish. Are you looking for a particular NMN dosage? Do you want to mix other ingredients for anti-aging? What are the current obstacles to your health?
It is crucial to keep in mind that NMN supplements aren’t the magical elixir for youthfulness. There are a lot of other, arguably more important elements for good health.
CHECK INGREDIENTS CLOSELY
The most effective NMN products do not just have high purity NMN However, they must also stay clear of the use of any synthetic additives. If you’re buying NMN supplements there’s more than just NMN that you should be thinking about. Does it contain fillers or other additives such as magnesium or stearate? Are the capsules made of animal-derived gelatin or vegetable cellulose? Are there any other surprising ingredients mentioned?
All of this is important when you’re trying to assess various brands. It’s difficult to discern most times because the information is typically listed in tiny printed on the label’s back.
LOOK FOR DISCOUNTS
NMN supplements vary between $30 and $100 bottles to well over 100 dollars per bottle. Most of the supplements mentioned above have a price in the range of $50 to $90 for a single month supply.
A lot of companies offer special discounts to new customers, or when you purchase multiple packs.
NMN supplements are intended to be consumed continuously. It is extremely unlikely that you’ll see any changes in several weeks, which is which is the reason you won’t you have a 6-pack after working out for one month.
LOOK FOR MONEY-BACK GUARANTEES
Check for guarantees on your money back, which provide another layer of protection in case you decide that NMN isn’t for you. The brands we’ve selected provide a 100% money-back guarantee. The most trusted brands will always stand behind their products and their products.
LOOK OUT FOR FAKES
NMN is a costly ingredient. It’s not as cheap as the standard vitamin C or B complex that you could purchase at low prices on Amazon. It comes at a high price. You might come across NMN supplements that are inexpensive, but you should always be skeptical about the quality and accuracy of their products.
CHECK REVIEWS
It’s worthwhile to look at customer reviews online and on the company’s site to see how other customers review these brands. Be aware that some reviews might not be authentic, and others could be negative. But, in general you will discern how a company’s reputation stacks up by analyzing others’ experiences.
HOW TO GET THE BEST RESULTS WITH NMN SUPPLEMENTS?
NMN isn’t a magic supplement that will help you achieve your health and longevity objectives. There are a variety of life-style factors that can boost NAD+ levels in a natural way, which should be considered in conjunction with using NMN supplements.
This includes:
DIETARY RESTRICTION (AKA INTERMITTENT FASTING)
The study suggests that NMN increases NAD+ levels that stimulates cell repair mechanisms. Fasting is also responsible for activating autophagy, which rids cells of proteins that are dysfunctional. It is essential to speak with your physician before you start since fasting might not be appropriate for you.
HIGH-INTENSITY EXERCISE
Every exercise program is beneficial to you, but studies have shown that intense exercise can be particularly effective at activating genes that promote longevity. It’s basically bursts of intense activity, with a period of relaxation in between. If you’ve ever attended an HIIT class, you’ll be aware the basics of this!
IMPROVE SLEEP QUALITY
Sleeping better is the single factor in your lifestyle which will have the most impact on your longevity. A better night’s sleep has been linked to better overall health and a reduction in every causes of death.
OPTIMIZE DIET FOR LONGEVITY
If you’re thinking of purchasing NMN supplements, then you might be interested in other aspects that comprise your food. The ideal diet for long-term health is the subject of ongoing research and there’s no “one-size-fits-all” strategy. Studies suggest that following an “Mediterranean diet” that has the primary protein intake coming from fish, rather than other meats is advantageous.
NMN SUPPLEMENT SIDE EFFECTS
Most NMN supplements are secure because they are naturally produced within all cells. However, like any supplement, negative consequences are possible, and a few studies have found slight negative effects.
The most commonly reported is stomach upsets, which could mean things like stomach pain or diarrhea. Others are headaches and flushing which is a redness of the face.
In any event it’s best to speak with a medical expert prior to taking any new supplement, particularly when you suffer from any other health issues or are taking medication.
WHAT ARE THE DOWNSIDES OF NMN?
Although there is some promising research regarding the benefits of NMN however, there are possible negatives. For instance, the study of NMN is in its early stages. While significant benefits have been observed in animals, benefits for humans are being studied.
Apart from that it’s also a costly supplement. NMN is created through a variety of chemical processes that range through vitamin B3 until NR and the final NMN that makes it a complex.
In the end, we’re not sure what the ideal dosage for NMN is. It’s likely to differ dependent on your particular situation and objectives.
FAQ’S
Here are a few of the most frequent questions that people ask concerning NMN supplements:
IS NMN BETTER THAN NR?
NR can be described as the precursor to the NMN. Therefore, NR is a step more than NAD+.
Research studies have proven that NMN and NR increase NAD+ levels. However, there aren’t many studies comparing them directly.
Scientists think that NMN is superior because its closest is NAD+, the direct precursor, and thus only 1 step from NAD+. The more closely a molecule is NAD+ it is, the less energy our cells must use to make it.
IS NMN BETTER THAN RESVERATROL?
Contrary to the comparison of NMN to NR It is harder for comparisons to be made between NMN to Resveratol, as they’re very distinct substances.
Resveratrol is a plant-based, naturally occurring polyphenol that is also an antioxidant. While NMN is an vitamin B3 derivative, which is found throughout our cells.
The anti-aging properties of Resveratrol is attributed to the fact that it is an activator of sirtuin. This is a family of enzymes which are involved in the process of cell metabolism and the process of aging. Additionally, Resveratrol has been proven to increase sirtuins’ activities and in turn increase NAD+ levels.
The primary function of NMN is to increase NAD+ levels. However, Resveratrol boosts NAD+ levels in a more minor degree however it also has benefits, such as antioxidation or anti-inflammatory properties.
This is why a few of the top NMN brands also contain Resveratrol, which is a powerful anti-aging supplement.
DOES NMN MAKE YOU LOOK YOUNGER?
In the end, it’s unlikely that NMN can make you appear older because hair and skin ageing is a result of many external influences. Sun damage, cumulative and the reduction in collagen after time are the primary reasons for wrinkles.
However there are reports of people claiming that their gray hairs become darker after having taken NMN supplementation for just a couple of months.
WHICH NMN SUPPLEMENT DOES DAVID SINCLAIR USE?
Harvard Professor Dr. Sinclair is perhaps one of the most well-known advocates for the NMN supplement. His research has established NMN as one of the most effective supplements for healthy aging. He has stated that he consumes 1000mg of NMN and 1000mg of Resveratrol daily.
However, he doesn’t specify the particular NMN brand he’s using. The specific NMN supplement David Sinclair takes is not that crucial. All that is important is if it’s NMN purity is good and is from a trusted manufacturer.
CAN I TAKE NMN ON AN EMPTY STOMACH?
If you’re a practitioner of intermittent fasting, you’ll need to be aware of whether you can take NMN with a full stomach.
The answer is yes, you can. NMN is well absorbed through the intestines, even on a stomach that is empty.
Certain people might experience stomach discomfort while using NMN with a full stomach. In this instance, having it along with food may help alleviate this issue. But the vast majority people will not have problems taking NMN when they are not hungry.
WHAT IS THE BEST AGE TO START TAKING NMN SUPPLEMENTS?
There isn’t any recommended ideal age at which to begin using NMN supplements. It’s entirely up to you that is based on your personal preference and objectives.
NAD+ levels begin to decline around the age of 20 and increase by the time we hit 50. This is why some recommend starting earlier rather than later. However, this is an individual decision.
WHY NOT TAKE NAD+ INSTEAD OF NMN?
In the course of this piece, we’ve stated that the primary purpose in NMN supplements is to increase NAD levels. You might be asking what’s wrong with taking NAD+ rather than NAD?
The reason for this is that NAD+ isn’t taken directly from the gut because it’s a vast molecules. It’s broken down, and then absorbed by vitamin B3 and other constituents. This isn’t efficient, and is far less effective in boosting NAD levels.
HOW SHOULD YOU FEEL AFTER TAKING NMN?
There’s a lot of anecdotal evidence that suggests taking NMN supplements can increase your energy levels and more able to work harder while exercising. There are also studies that support this in the case of assessing fitness performance following the use of NMN.
In reality, people will not feel any significant change if not for a few months. NMN is designed to function at a cellular scale, and expecting a massive shift in mood is unrealistic. The evidence of any benefits can be seen in the tests to determine one’s age at birth.
CAN I TAKE NMN WITH OTHER SUPPLEMENTS?
In simple terms, the answer is a resounding yes. NMN isn’t recognized to interact with other supplements. It is in fact the product from vitamin B3. This means that there shouldn’t be an issue if it is taken in conjunction with other supplements.
NMN is frequently mixed with other ingredients such as Resveratrol, CoQ10, Quercetin, and Trimethylglycine to mention just a few.
If you’re contemplating taking NMN together with other supplements, you should be sure to test it on your own by taking one supplement at a time instead of taking a number of. This way, you’ll be able to determine how you react to each one.
BEST NMN SUPPLEMENTS CONCLUSION
There you go we have concluded our analysis of the top NMN supplements available.
We’ve given you a rundown of some of the most important aspects to be looking for when purchasing NMN supplements. We’ve also chosen a selection of the most popular NMN manufacturers available today.
There are a variety of great options available as that you ensure that you choose an authentic brand that is made of the highest purity NMN which is produced in a GMP certified facility, with no additives.
